JS: Put simply, while marijuana and hemp are both plants of the same species, Cannabis Sativa L., hemp is different in that it contains only minute levels of the cannabinoid THC, which is the one that produces a psychoactive effect. Marijuana is high in THC, while hemp is high in non-psychoactive compounds like CBD. Hemp and CBD are also legal federally, while marijuana is legal only in certain states. HJ: It is important to use caution with any new product that you have not used before. There are many factors to consider, such as where and how the plant was grown, how the product was processed and manufactured, and the route of administration used. Someone could have a sensitivity to a regional allergen, plant nutrient, herbicide, pesticide, mold, mildew, or other contaminant in a marijuana product that could be absent in a different CBD product. Furthermore, because CBD is nonaddictive and does not bind to receptors, it is safe to stop use immediately or “cold turkey” without the fear of withdrawal side effects. Finally, even though withdrawal effects are absent, if one discontinues the use of CBD, of course symptoms could return if CBD was previously helping.